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Monday, August 3, 2020

Emerging drugs for the treatment of light chain amyloidosis

Systemic AL amyloidosis is a protein-misfolding disorder that is characterized by the deposition of insoluble amyloid fibrils derived from kinetically unstable light chains. Achieving a rapid and deep hematologic response is critical for long-term survival.

This review covers the existing and emerging treatment options for systemic AL, divided into anti-plasma cell and fibril-directed therapies. Click here to read more.